Chondroitin sulfate biosynthesis
| PAG Title | Chondroitin sulfate biosynthesis |
| PAG ID | WAG000383 |
| Type | P |
| Source Link |  KEGG |
| Publication Reference | NA |
| PAG Description | Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide units and form proteglycans by covalently attaching to their core proteins. Chondroitin sulfate (CS) is a glycosaminoglycan with the disaccharide unit of beta-D-galactosamine (Galc) and beta-D-glucuronic acid (GlcA), and often modified with ester-linked sulfate at certain positions. Dermatan sulfate (DS) is a modified form of CS, in which a portion of D-glucurote residues is epimerized to L-idurotes (IdoA). CS and DS are linked to serine residues in core proteins via a linkage tetrasaccharide formed by the transfer of xylose and three more residues [MD: |
| Species | Homo sapiens |
| nCoCo Score | 952 |
| Base PAG ID | WAG000383 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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